Our Platform

Viscoelastometry involves real-time analysis of clot formation in whole blood, allowing concurrent assessment of multiple aspects of coagulation including clotting factors, platelets, fibrinogen and fibrinolysis. Tests can be performed rapidly, supporting prompt identification and characterization of coagulopathy and anticoagulant effects. This enables focused, rational and timely administration of therapies such as blood products, and the effects of treatment can be monitored as required.

Applications

Viscoelastometry is widely used in clinical conditions where coagulopathy and bleeding are of concern. These include trauma, major surgery (e.g. cardiovascular procedures) and obstetrics. Clinical use of viscoelastometry is advocated in guidelines from national and international societies and is regarded as best practice by many institutions.

A wide portfolio of assays allow detailed and cost-effective assessment of haemostasis:

rapid overview of the coagulation process including clot formation and clot stability (speed of fibrinolysis), following activation of the extrinsic pathway by recombinant tissue factor

assessment of the coagulation process following activation of the intrinsic pathway by ellagic acid

heparin-insensitive test, performed with heparinase and intrinsic activation by ellagic acid

assessment of clot formation with tranexamic acid for fibrinolysis inhibition, with extrinsic activation by recombinant tissue factor

functional determination of fibrinogen status with a dual platelet inhibitor

rapid detection of FXa antagonists, with coagulation activated by russel viper venom

heparin-insensitive assay for the detection of FXa antagonists

rapid detection of dabigatran, with coagulation activated by ecarin

detection of fibrinolysis inhibition by tranexamic acid using recombinant tissue plasminogen activator (t-PA), with extrinsic activation by recombinant tissue factor